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In trials 1, 2, and 3, Semaglutide or a similar placebo was shot up to 2.4 mg once a week, subcutaneously in the 16 weeks, and this was followed by 52 weeks of maintenance dose

While GLP-1 therapy is highly effective in reducing appetite and improving metabolic function , the speed and success of weight loss are also influenced by diet, exercise, and overall lifestyle

Both drugs lower blood sugar and A1c levels, improve insulin sensitivity, decrease insulin resistance, and may lead to weight loss

5,6 It also inhibits tyrosinase activity and melanosome transfer from melanocytes to keratinocytes

some research suggests that the human body doesnt seem to like losing weight and actively works against it